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t 01:00 PM 6/29/97 -0400, you wrote: >currently I take one 10/100 kick starter in the AM >followed by one 25/100 CR, one eldepryl and 1 mg permax and one artane an >hour and half later; >four hours later I repeat one 25/100 CR, one eldepryl, and 1 mg permax; >3 -4 hours later I repeat all (except the eldepryl). My information (from Neuro) is that only 60% of slow release levadopa makes it to the brain. Also takes longer to get there 1-2hrs. depending on individual. So going by your meds. regime I don't think your getting enough levedopa. Especially since you are not experiencing any dyskinesia. I don't take any agonists drugs and my meds go like this. 100mg kick start am.then( 200CR & 100mg ordinary levedopa) repeated four hourly. I do titrate the 100mg. ordinary levedopa according to level of activity. eg. on a lazy afternoon I can tell by meds time by how I feel wether I can do without the 100mg. ordinary levedopa. But I keep the slow release to every four hours and this provides the steady flow. Of course every-one case is different and I made a choice not to take agonists at this stage but rather opt for the higher levedopa path. I know all the arguments for and against this path. Hope this is of some help to you. Regards Mary from Aussie. [log in to unmask]