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Donna Kipp <[log in to unmask]> wrote: <<HELP!! I am 50 and have been diagnosed for almost 11 Years and for the last couple of week I have been plagued with daily sometimes more periods of 3 hours of dyskinesis. It is totally exhausting!! During these periods I usually keep walking or can rest in my recliner. This is totally taking over my life!! I am willing to try any or all suggestions. I am unable to correlate it to either over or under medication. I think it is diphasic. I am taking 3- 50\200 CR, 3- 1mG Permax and 1eldepryl. I tried cutting out the permax. Increasing Sinemet, decreasing Sinemet. I am ready for any and all snake oil...Donna>> I suggest you try taking half a 10/100 carbidopa/levodopa every two hours from awaking until an hour before sleeping. Try to take only small meals 30 minutes after each half-tablet. If you wish to see some basis data for this recommendation, visit my home page and links "effective period" and "pharmacokinetics" at least. URL below: http://www.ridgecrest.ca.us/~rfvetter/ Ron Vetter - NOT a doctor.