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On Tue 08 Jul, ROBERT NAYLOR wrote: > Hello Donna. > > I usually stay in the background as far as the list is concerned, but > when you mentioned your 4 hours of dyskinesia I felt that I had to say > something. > > If my wife takes sinemet Cr late in the day (past noon actually) she has > the same problem. However, by switching to regular sinemet her dyskinetic > period is 15 minutes or less. (Average about 10 min) > > Think about taking sinemet as an airplane ride. You take off and fly > through the clouds. While going through the clouds there is some turbulence, > but soon you burst into the sunshine and the going is smooth until evening. > Now you have to land. You can dive through the clouds or you can coast down > gently. By diving through the clouds you get out of the bad time quickly. > However, if you go down at a gentle slope, it takes a long time to get > through them. > > Slow release often lets you down so gently you have to spend a long > time in the clouds. > > The other trick that we have is to relax as soon as the dyskinesia > starts. My wife lays crosswise on the bed with her legs over the side and > her head on a pillow. If you strain in any way during the dyskinesias they > just last that much longer. > > Hello Bob, It's nice to hear from you again. I have experienced end-of-dose dyskinesias myself recently, as part of my efforts to find out what it is all about, and most unpleasant they are too. However, I have also found out how to avoid them, so I don't go there any more. Your comments are useful, because up there in what I call 'The Twilight Zone' the rules which I have derived for my analysis program simply don't work. Your rule that if you come down fast, the period of Dyskinesia is shorter agrees with a comment someone else made (But she is not talking to me any more). I tried to work through the dyskinesia last time, and if did seem to last a long time, so if I inadvertantly get into that condition again (and its very easy to do so), I will try to relex like your wife. Best Wishes, -- Brian Collins <[log in to unmask]>