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Bruce, I just found out, that my father's neurologist, who has always been very conservative, and unwilling to try anything he is not well versed on, is going to check out dad on the 8th of August, in relation to trying Mirapex. I know this is not a guarantee that he will be started on it, but I am anxious to see what happens. From what I have read here, the worse the symptoms, the more it helps. Dad is 80 and really needs all the help he can get. I saw a question about changing from Permax to Mirapex, implying it is a problem, do you know if this is the case? Thanks, Ken B