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For those who have been living with PD longer than I, is there an average speed and order for the onset of different symptoms? I know the answer is probably no, but I would be interested in hearing from some of you as to how you got to the place you are at now. Nearly 4 years ago I started my slide to the bottom of clinical depression. Nearly two years ago my tremor started in my right hand. At first I wanted to say it was just because I cried a lot and was depressed. One doctor thought it was the paxil that caused the tremor because it can in some people. But, when I went to the neurologist one +one/half years ago, he poked me, watched me walk, checked out my tremor, and said that I had PD. The tremor alone would not have been enough, but when he was testing my muscles I exhibited the "cog wheeling" effect of muscle ridigity. These combined with my depression started me on eldepryl and sinemet. I reacted nearly immediately to the sinemet. This only confirmed it more. Since my diagnosis, the tremor has spread to my right leg. I have cramps ( not ordinary type, but PD tightening of muscles) in both my right calf and thigh and this week in my left calf. I have some stiffening, lose of balance, shuffling or limping, and now I think my left arm is beginning to tremor also. I have had a "tic" in my lower lip for many years and I suppose that was really one of the very first symptoms, but went unreconized. How have some of you progressed?? I am curious as to this progression, the order of symptoms and speed. Thanks for reading my too long post, and I hope some of you will answer in kind. don't forget how to laugh Marling [log in to unmask] (work) or [log in to unmask]