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My father, Walter, is 84 years old and takes Eldepryl and Sinemet. My mother and I have experienced benefits from an antioxidant called pycnogenol (proanthocyanidin from the Maritime pine tree) and we have finally talked Dad into giving it a try. But he is very skeptical. He is building up slowly, as anyone just starting out should, but says he feels worse, not better and will stop if he doesn't start to feel better soon. We know from personal experience and the experience of others, that a "cleansing" of the body occurs when first taking this compound, and it is not unusual for someone to feel worse at first. Loose stools are also a common side effect. But these soon go away and, after reaching the full dosage, the benefits start to become obvious. In my case, my ADD-type of fuddled brain cleared and I was much more able to think clearly. My arthritis and carpal tunnel left. I felt better than I had in a long time. Dad would be much more likely to stick with pycnogenol if he knew another PD person out there had tried it and had benefitted. But there is a dearth of information on the subject of pycnogenol and PD. Has anyone out there tried this? We would so appreciate an answer. Thank you. Audrey Beust McMurray