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Mary, You wrote: >> The second engineer nodded approvingly "Good choice, >> the clothes probably wouldn't have fit. I obviously went to the wrong engineering school. I had female engineering classmates that would never have given up the bike and were very selective about who they tore their cloths off for, but what would life be without fantasy. :-) I hate to interject something halfway serious here, but it plays into something that has been on my mind. The effects of male hormones on PD symptoms and medication effectiveness. We have somewhat addressed this topic for women here on the list, so I'll put something forth to ponder. I would frequently study under a favorite shade tree during summer sessions at university. Everything would be going along nicely. I would be making great progress completing those nerdy engineering assignments. Along would come a well endowed yound lady in tank top and short shorts. Mental capacity would be obliterated unlike the sterotype in your joke. Testosterone can make pretty intelligent men do some stupid things. This is both observation and experience. I know you are saying, "so O.K. Phil you have stated the obvious". Well what does testosterone do to those neurotransmitters to cause this temporary dementia? What other neuro transmitters does it affect? We lose muscle mass and tone in our forties as a result of reduction in testosterone levels. I know we PD types are supposed to suffer from hypotonia (sp?), but could appearance and severity of symptoms also be related to this reduction in testosterone? Is this related to the beneficial effects of exercise in relieving symptoms. Some seem to have the urge to trade in loving companions for trophy wives. So lower testosterone levels might also contribute to another form of dementia - TDS (Testosterone Depletion Syndrome). Maybe this is longer term. Well Mary, thanks for your post. Brain storming - almost as good as fantasy. Phil G. 47/1+ [log in to unmask]