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Dave Garboczi wrote: > > Dear all, my father (75 / 7 yr diag) tells me he does not feel a > kicking-in after he takes a Sinimet. He says he doesn't feel anything. > Dear Dave, 1)Has a movement disorders specialist diagnosed your father with idiopathic Parkinson's? 2)How long has he been using Sinemet? 3)Has the response always been the same, or is the "non-response" new? 4)Does he take the Sinemet on an empty stomach? 5) Does he take Sinemet or Sinemet CR? As you say you are not satisfied with his neurologist, I'm wondering if the neuro is a specialist in PD, which can make a great difference in both diagnosis and treatment. If your father has been taking Sinemet for 7 years, with no response to Sinemet, perhaps you need a second opinion. However, if he has responded to Sinemet in the past, and the non-response is relatively new, his medications may need to be adjusted. And, finally, if he takes Sinemet with his meals, response can be altered considerably. It is preferable to take both Sinemet and Sinemet CR on an empty stomach, although the CR can be used with food. Also, CR may have less of an effect than regular Sinemet. Best regards, Kathrynne -- Kathrynne Holden, MS, RD Editor-in-Chief, "Spotlight on Food--nutrition news for people 60-plus" http://www.fortnet.org/~fivstar and NUTRITION TOPICS copy-ready handouts http://www.dietetics.com/class/fivstar/ Tel: 970-493-6532 Fax: 970-493-6538