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Hello again, I'm glad the Amitryptyline Hydrochloride is working for you, and that your basic positive attitude is intact. So far I have no depression, but I do have insomnia. I suspect it's an effect of levodopa. Sometimes I wake up just about every hour. I took my first dose of Ambien (zolpidem) last night and slept better. I'll report on its effects after I have more experience with it. Phil T. 59/6 Hoboken NJ ron d wrote: > Phil wrote > "Were there other indications that you were depressed? Although PD > frequently causes depression, and depression can cause insomnia, > insomnia can have other causes besides depression." > > There were a couple of other indications. Firstly a feeling of > general sadness at something lost in my life. Could'nt pin down > exactly what I thought I'd lost. The feeling would last a couple of > hours hours and I'd have to work hard at mentally blocking this > negative feeling with positive thoughts. Secondly when first > awakening in the morning I would get a mental picture of hanging > myself. This was'nt too hard to get rid off: just replaced the image > with thoughts of "Lets fight this PD and never give in!" > > Two points to keep in mind. > 1. I have a positive type of mind and before PD never had > depression. 2. Since taking the Amitryptyline Hydrochloride 25mg at > night and getting a reasonable nights sleep it is much easier to > mentally block negative thinking.