GatorGal78 wrote: "Have written before re; my spaciness, but decided to try again. It is limiting my ability to lead a "normal' life. Feel like i'm the only person in the world with these symptoms--only way describe them is to say I feel as if i were very high(stoned ) not a pleasant feeling at all, can't thiink that well most of the day, my coordination is off --- feel like a total space queen--feel totally out of if. I'm only 55 yrs. old, am taking 25/l00 sinemet a whole one at 6a.m. and 6p.m. and a half every two hrs. the rest of the time. take a 5mg. elderpryl at breakfast and at lunch. I think it's due to the medicaton but my doctor doesn't agree with me. Does aybody have any ideas, thoughts--- am getting desperate to find a solution... Hope this will shed some light..... --------------------------------- SIDE EFFECTS OF SINEMET (LEVODOPA) --------------------------------- + Nausea and vomiting, as well as vague symptoms of gastrointestinal discomfort, which usually subside after weeks or months of treatment + Constipation that can cause discomfort and may require a change in diet or a special bowel program + A drop in blood pressure, the primary symptoms being those of light-headedness, dizziness, neck pain and/or increased imbalance + Increased sleepiness, particularly following the morning and afternoon dose of medication + Increased nightmares, hallucinations and confusion during the later part of the day or at night. -------------------------- SIDE EFFECTS OF ELDEPRYL --------------------------- + Nausea, stomach upset, light-headedness + Insomnia, especially if taken after 1 or 2 pm + Confusion, hallucinations and nightmares (more commonly encountered in older patients, or those who have had Parkinson's for many years) + Occasionally Eldepryl may worsen dyskinesias or cause other side effects similar to those of levodopa excess cold, clammy skin); nausea and vomiting (severe); stiff or sore neck. Check with your doctor as soon as possible if any of the following side effects occur: More common: Increase in unusual movements of body; mood or other mental changes! Less common or rare: Bloody or black, tarry stools; severe stomach pain; or vomiting of blood or material that looks like coffee grounds; difficulty in speaking; loss of balance control; uncontrolled movements, especially of face, neck, and back; restlessness or desire to keep moving; or twisting movements of body;difficult or frequent urination; dizziness or lightheadedness, especially when getting up from a lying or sitting position; hallucinations (seeing, hearing, or feeling things that are not there); irregular heartbeat; lip smacking or puckering, puffing of cheeks, rapid or worm-like movements of tongue,uncontrolled chewing movements, uncontrolled movements of arms and legs; swelling of feet or lower legs; wheezing, difficulty in breathing, or tightness in chest. Symptoms of overdose: Agitation or irritability; chest pain; convulsions (seizures); difficulty opening mouth or lockjaw; dizziness (severe) or fainting; fast or irregular pulse (continuing); high fever; high or low blood pressure; increased sweating(possibly with fever or cold, clammy skin); severe spasm where the head and heels are bent backward and the body arched forward; troubled breathing Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common: Abdominal or stomach pain; dizziness or feeling faint; dryness of mouth; nausea or vomiting; trouble in sleeping. Less common or rare: Anxiety, nervousness, or restlessness; blurred or double vision; body ache or back or leg pain; burning of lips, mouth, or throat; chills; constipation or diarrhea; drowsiness; headache; heartburn; high or low blood pressure;inability to move; slow or difficult urination; frequent urge to urinate; increased sensitivity of skin to light; increased sweating; irritability (temporary); loss of appetite or weight loss; memory problems; muscle cramps or numbness of fingers or toes; pounding or fast heartbeat; red, raised, or itchy skin; ringing or buzzing in ears; slowed movements; uncontrolled closing of eyelids; taste changes; unusual feeling of well-being; unusual tiredness or weakness. Everyone is different...some experience no side effects and others may recognize one or more in this group that they experience. Why not ask your doctor if you can temporarily stop the Eldeprly to see if it is a contributing factor to the spaciness you are troubled by? Good Luck, Gail Vass email [log in to unmask]