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In a message dated 97-08-05 13:13:09 EDT, you write: << I have "wearing off" periods - so I have to try something new. >> My Barbara is close to that too, and our neuro is waiting a four or five more weeks, and if no improvement with the increased dosage of Sinemet, the route will like be Pramipexole (Mirapex) and/or Amantadine. She also told that she could be a good candidate for Pallidotomy - which shocked her. I dread the day... Support the Udall Bill, and hopefully... the eternal optimist... Live and Love says Auntie Mame... Michel