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On Fri 01 Aug, Arthur Stienstra wrote: > TO ALL. > My wife is taking APOMORPHINE along with all the usual PD medications along > with Zoloft and Clozaril. Add to that the over the counter stuff for > constipation. > If anyone else is familiar with the use of Apomorphine, I would like to > exchange info with them. She is also trying the new medication PRAMIPEXOLE > (TRADE NAME: MIRAPEX). She has had PD for about 15 years. > [log in to unmask] Art Stienstra > > > Hello Arthur, Apomorphine is indeed a potentially powerful drug. I tend (Like Ida) to think of it as a little 'nest-egg' for the time when virtually nothing else will work. I know one person who uses Apomorphine on an occasional basisS, and reports that sometimes it can induce extreme sleepiness, even to the point of flopping face down into the evening meal ! I don't know if you are aware of it, but there is an alternative method of delivery for Apomorphine: The Apomorphine pump, This has to be plugged into the body at the beginning of the day, so it is not entirely free of injections (These injections are, by-the-way , into muscular or fat areas, NOT into veins. The nice thing about the pump system is that it delivers just the required quantity of drug, and, because it by-passes the food route altogethere, is unaffected by meals. I can't tell you the price, but it is NOT cheap. One last point, you seem to be trying very hard to find a resolution of your problems and as one who was diagnosed 18 years ago, I can sympathise with your problems. However, don't rush into anything, and don't change more than one aspect at a time, otherwise you may miss the next important change. Regards -- Brian Collins <[log in to unmask]>