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Marling, The effect of Eldepryl is twofold. First of all, it is a mono amine oxide inhibitor. Mono amine oxide scavenges used dopamine and by inhibiting its action, there is more dopamine left. The second effect is less certain. Eldepryl supposedly slows down the progression of Parkinson's disease, but to the jury is still out on that one. Since Eldepryl does not really increase the amount of dopamine, there is no improvement in symptoms from using it. That is why you did not notice any improvement when you took Eldepryl by itself. The actual effect in this case was probably to reduce the rate of degradation. Bruce 55 / 9 * The above message dictated using NaturallySpeaking *