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Joan, I have been taking Fosamax for about a year and a half. The only PD med I take is Eldepryl (5 mg). I also take 1500 mg of Calcium per day. I have had no problems with Fosamax, except in the first week when I had stomach pains - a common side effect. I had a recent bad fall (11 stitches and a severed nerve in my forehead, plus two very sore knees and assorted cuts and bruises) but no broken bones! Hopefully, the Fosamax is working well because Osteoporosis is a really nasty disease. Mary Sheehan ([log in to unmask])