In answer to Carol Gray, >>Date: Wed, 6 Aug 1997 06:04:17 -0400 >>From: "W.Carol Gray" <[log in to unmask]> >>Subject: mirapex >>My neurologist told me to start cutting down my permax oveer a six >>week pereiod and at some point I would probably have to be >>hospitalized to finish the process and then go on mirapex. that >>sounds dangerous to me (3 mg. permax daily). has anyone else been >>told this? I was at my mom's PD specialist, Dr. Fazzini last week. He has been involved in the Mirapex(Pramipexole) testing for the last 4 years at New York University, and says that he has many patients already on Mirapex since it has been approved by the FDA. He told her to switch immediately from the 3 and 1/2 mg. of Permax daily, to 5 mg. of Mirapex. Instead of taking .75 permax 4 times a day, she is to use 1 mg. of Mirapex, and for the last .5 of Permax, she is to use 1/2 mg. of Mirapex. She (80,6) started this regimen on Sunday, three days ago, and has had no side effects. She even went to her senior center today without a cane. Until now, she has been too frightened to try it without a walker. Now, I don't attribute this big change just to the Mirapex. About 2 months ago she started on 5 siminet (25/100) a day, and started seeing big progress then. I think she just finally feels so much better because of the last few months (plus whatever Mirapex adds) that the 2 drugs together are giving her a greater sense of confidence in her balance. She has been able to take the sinimet because she takes 2 motilium with each pill to help get rid of the nausea that used to prevent her from taking sinimet. She will try to move down to only 1 motilium at a time in 2 weeks, and see how that works out. [log in to unmask]