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At 09:13 AM 8/10/97 -0400, Ernie Peters wrote:

-snip-

>3. A current medical site I have read, comes up with this interesting quote:
>
><<The half-life of deprenyl in the body is only a few hours; but once it
>enters the brain, its effects are very long-lasting. The half-life of MAO-B
>inhibition in humans has been measured to be about 40 days, therefore,
>deprenyl probably need not be taken daily by persons who do not have a
>neurological disease.>>
>
>This would probably account for the fact that it took a number of weeks for
>the effects of my withdrawal from Eldepryl to become noticeable.
>

Ernie, we are all warned to take an Eldepryl holiday for several weeks
before having an operation when Demerol or another drug incompatible with
Eldepryl might be used.

If the effect of Eldepryl has a half life of forty days, shouldn't we
wonder if a two or three week holiday is long enough?

Art

Arthur Hirsch [] [log in to unmask] [] Lewisville, TX
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