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Tom Riess and others-- thanks for the suggestion that the Mirapex +Sinemet might be the problem. Our neuro refused to reduce the Sinemet right away, but I did ask--he feels Peter has alwaysbeen undermedicated. I will sask him about this, but am very leery of Mirapexfor Peter now. As of tonight he was really freaked out, combative with the nurses, not even trusting me. It is terrible for both of us, needless to say. I pray when the Mirapex is out of his system he will return to his usual gentle loving self. I still hope others can benefit--but just watch carefully! AND THANKS TO ALL THE WONDERFUL PEOPLE WHO HAVE SENT MESSAGES OF ENCOURAGEMENT--SO MANY--A REAL BLESSING. Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio [log in to unmask] * * * * * * * * * * * * * * "Ask me about the CARE list for PD caregivers!" * * * * * * * * * * * * * *