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Don--tell your neiro that it seems the key to good luck with Mirapex MAY BE cutting back on Sinemet RIGHT AWAY. We think Peter got an overload because that was not done. Good for you that you are supplying him with info, and good for him for listening! Not all will do that! IYQ 2, Camilla Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio [log in to unmask] * * * * * * * * * * * * * * "Ask me about the CARE list for PD caregivers!" * * * * * * * * * * * * * *