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Dear Ron Audrey and I both took grape seed extract for about a week or ten days and had a very bad experience with stomach cramps. She also broke out with ulcers in the mouth. The stomach pains were not the ordinaary kind of upset stomach but severe burning sensation. She is also taking pycnogenol and likes it very much but the grape seed content is very minimal. The main ingredient is the maritime pine and she claims it helps her to think clearly. I swore off anything with grape seed extract after that ex perience. Good luck with yours. Cloverdale