Dennis G.... (Yawning) <grin> I'm not taking Mirapex yet 'cause it won't be on my HMO's formulary for another coupla weeks, so that's not the cause of the daily drowsiness. Also, since my pallidotomy, I really don't have on/off times in the traditional sense (thank God!). It sure can't hurt to have a thyroid test tho, and I'll make a point of getting one and will report back to the List if that turns out to be the cause of the problem. My gut feeling tho, Dennis, is that this IS somehow PD related, and not necessarily due to any of the PD drugs. I'm inclined to think it's part and parcel of whatever's going on in our respective brains. Barb Mallut [log in to unmask] ---------- From: Parkinson's Information Exchange on behalf of Dennis Greene Sent: Monday, August 18, 1997 6:48 AM To: Multiple recipients of list PARKINSN Subject: Re: drowsiness/possible causes Dear sleepyheads, Reading the range of responses to this thread I suspect that the causes of the episodes of drowsiness reported are in fact very different. Possible causes are: 1. Those experiencing drowsiness since commencing mirapex may be experiencing the drowsiness associated with moving from 'off' to 'on'. In this case the desire to sleep is triggered by the body relaxing in response to the medication. This reaction has been discussed on this list at some length. Perhaps those with a good response to mirapex are truelly relaxing for the 1st time in years. Chewing gum has been mentioned as a means of staying awake. 2. Those experiencing drowsines at a specific time, especially if it is in in the late afternoon should consider asking their doctor for a thyroid test. For many years my wife would nod of on the sofa at 4pm every afternoon. It was even dubbed her '4 o'clock special'. Since commencing thyroxin some years ago the problem has vanished. 3. Those experiencing drowsiness immediately after lunch may need to take their PD meds 30 mins or so before eating. Dennis. ++++++++++++++++++++ Dennis Greene 47/10 [log in to unmask] http://members.networx.net.au/~dennisg/ ++++++++++++++++++++