Hi! Is there someone on the list who takes 4 Madopar HBS (resp 4 Sinemet CR 25/100) per day? My father's neuro recommended to take 2 Madopar HBS in mornings and 2 Madopar HBS in evenings but we think that it's not quite right - father's feeling is not better than he took 3 regular Madopar per day. Maybe 2 capsules together (50/200) is too much for him and the period between the other 2 is too long? What do you think when and in which order these drugs have to take? Or maybe its better to combine Madopar HBS with regular Madopar '125' (resp Sinemet CR with regular Sinemet 25/100)? Any ideas? Thanks (In Estonia PD is rare and the greater part of neuros have little experience in PD treatment.) Hille, daughter of Viktor 74/1