 |
 |
Brian, You wrote: >>The action of Permax is very slow. According to ny neuro, and I agree >with him, Permax taken over a period tends to form a 'raised platform' >from which the levodopa then does its short time-period thing. Looking >for the effect of a single dose of Permax in the hours following the dose >is doomed to failure - it's effect is so sluggish. Over the past few >years I have gradually raised the amount of Permax to offset my steady >deterioration so that I am currently taking 2.5 mg of Permax. I have had >no side effects, and the effect seems to be linear over the range 0 to >2.5 mg. Brian, When you say the effects are linear with dosage are you talking about side effects or effectiveness of treatment. If the time constant for Sinemet is in hours, what is your guess for that of Permax? Phil G. 47/1+