THANKS, Needed the run down the doctor has just prescribed this medication . However he was vague about when to take it etc... After reading all the messages on effects and what everyone is doing one gets a bit mixed up. Still sounds like in all this med that it will depend on the individual. However the postings seem to indicate that we all are getting better at administration of the med.. also seems that Mirapex is letting Pd.' decrease other med -- sounds good in most cases. Will let you know how it works here.. Will start after the holiday on the first week with possiable increases in the second.. ( not sure how tolerant will be of the meds - the doctor here said to try for the two and that if there is any problem to stop and re call him. specially if negative results. The patient here is working with a Mayo .Doctor.) Has any one got any information in "Deep Brain Stimulation " surgery.. Not specifically for tremor reduction .. Anyone been in the trial group and - what are the results and comments.... Thanks