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Brian, "...Fortunately, a newly-diagnosed PWP tends to be very tolerant to accidental over-dosing,..." What is "newly-diagnosed" mean? A few days, weeks, months, a year? I was diagnosed about 1+1/2 years ago and feel new to all this. However, I am NOT tolerant of accidental (or any other kind of) over-dosing. It hurts and was miserable. I am under medicated now and feeling it. I want to take more sinemet because it works, however,the side effects are more than I can stand. don't forget how to laugh Marling at play: [log in to unmask] or [log in to unmask] http://www.geocities.com/Heartland/Prairie/4895 at work: [log in to unmask] http://www.humobldt.net/~shcrc/