Mel was only weaned and then very gradually from Permex AFTER beginning Mirapex. Heard a ND speak today and he said he was leaving the Permex alone for right now as he begins Mirapex on his patients. He is extremely knowledgable, has 1300 patients and all PD or Dystonia patients. He's involved in research and still is with some of the other emerging meds. Mary CG for Mel 76/11