At w Hope your Doctor has some considered advice for you. Gordon is on week 4 and we are staying at .375. His Sinemet has dropped to 8 25/100. It had already dropped after his surgeries so he is half as much as 3 years ago, when we were in dire straits. Anyway, the doctor went very cautiously, we see him in two months again. Perhaps smaller changes would help. Good luck..Thea Seese