JP.... uhhhhh.... actually, I don't KNOW what symptoms I have that are corrected by the Sinemet, exactly <surprised look on face>. I was told immediately after my pallidotomy that it was VERY important that I continue taking Sinemet after the surgery so have done so daily. Truthfully, I have no idea what symptom's show up if, say, I gradually weaned myself off the drug. Hmmm.... (thinking)... well, my eye muscles don't work real well tell I take my first daily dose of the drug. That's just happened this year... And yeah... 22 years with PD is sooooooo long! <HUGE sigh> Barb Mallut [log in to unmask] ---------- From: Parkinson's Information Exchange on behalf of Joao Paulo Carvalho Sent: Friday, August 29, 1997 6:21 AM To: Multiple recipients of list PARKINSN Subject: Re: Mirapex - To It or Not? Barbara Mallut wrote: > In the almost 22 years I've had PD I've only taken Sinemet (except for > 2 years > of taking Eldepryl in 1990 and '91) to treat it's symptoms. No > Permax, no > Parlodol, no amantadine... no other prescription drugs for the > disease. I > have had a unilateral pallidotomy for which I'm ever grateful. > > Since I stopped working last July, I've been able to cut the amount of > Sinemet > I'm taking to less than a third of the amount I took while employed. > This > means that since mid July I usually take 1/2 a Sinemet 25/250 twice a > day > (along with a multi-vitamin, additional vitamin E, and CQ10). > Sometimes I may > take an additional 1/2 Sinemet if I'm out late in the evening. That's > IT. Barb M, What simptoms do you have that are corrected by sinemet ? Do you have offs during he day or night ? Outch! 22 years is quite a time... :-) and I am optimistic too that they will come with some new real good drug to improve even more your symptoms. Best wishes, +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+