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I'm confused. Are the two excerpts quoted below saying the opposite of each other? Can someone pull the info on serotonin, dopamine, tryptophan, B complex, etc. together? ">>>>>>>>>..........I quote briefly the following for what it's worth: "There is both experimental and clinical evidence to suggest a role for serotonin in Parkinson's disease. Inpatients with PD, the concentration of total serotonin in CSF had significant negative correlations with Hoehn & Yahr' stages, and the severity of rigidity, akinesia, and gait freezing.......(also) tryptophan and papaverine, interacting with levadopa, may aggravate motor sympt oms in a parkinsonian patient ,but their capacity to induce parkinsonism by the mselves is uncertain." This suggests to me that one who is taking levadopa should be careful of tryptophan. Do others have info aboutthis effect?........" Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio<<<<<<<< >>>>>>>>>"............It is when the body's Serotonin levels drop that patients develop more serious akinetic symptoms... ................ It is for these reasons that physicians prescribe SSRI's (Selective Serotonin Reuptake Inhibitors) such as Prozac, Paxil, and Zoloft. In addition to these medications, Dr. Iacono recommends that all his patients take a B-complex vitamin AT NIGHT along with a Banana. Banana's, turkey, and peanuts are foods rich in tryptophan, a precursor of Serotonin which requires B vitamins to produce Serotonin.........." [log in to unmask]<<<<<<<<<<<<< Thanks to all who are helping me sort this out. It leads to other questions which I've had for some time, which perhaps will follow for discussion. I agree with Phil Tompkins statement, "....Understanding PD gives me a sense (or illusion?) of control......" Mary Legan