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Mary Legan wrote: > I'm confused. Are the two excerpts quoted below saying the > opposite of each other? Let me take a crack at it, although my knowledge is limited. The following says the less serotonin, the worse the PD: > "There is both experimental and clinical evidence to suggest a > role for serotonin in Parkinson's disease. In patients with PD, the > concentration of total serotonin in CSF had significant negative > correlations with Hoehn & Yahr' stages, and the severity of > rigidity, akinesia, and gait freezing The following says tryptophan [which gets converted to serotonin, but before that happens] may interact with levodopa to make PD worse. I wonder whether this is because tryptophan is a protein and protein interferes with levodopa: > .......(also) tryptophan and papaverine, interacting with levadopa, > may aggravate motor symptoms in a parkinsonian patient, but their > capacity to induce parkinsonism by themselves is uncertain." > This suggests to me that one who is taking levadopa should be > careful of tryptophan. Do others have info about this > effect?........" Camilla Flintermann, CG for Peter, 78/7, > Oxford,Ohio<<<<<<<< The following says to take your tryptophan in the evening [which is when I've seen it recommended to ingest the largest part of one's daily protein]: > "..........It is when the body's Serotonin levels drop that > patients develop more serious akinetic symptoms... > ................ It is for these reasons that physicians prescribe > SSRI's (Selective Serotonin Reuptake Inhibitors) such as Prozac, > Paxil, and Zoloft. In addition to these medications, Dr. Iacono > recommends that all his patients take a B-complex vitamin AT NIGHT > along with a Banana. Banana's, turkey, and peanuts are foods rich > in tryptophan, a precursor of Serotonin which requires B vitamins > to produce Serotonin.........." [log in to unmask] Is this the correct reading? BTW, exercise is supposed to raise the serotonin level. Phil Tompkins