Date: Monday, September 8, 1997 11:25:21 AM From: AOL News Subj: Muhammad and Lonnie Ali Share Personal Side of Parkinson's Battle Caregivers play essential role in bringing quality to patients' lives CHICAGO, Sept. 8 /PRNewswire/ -- Muhammad and Lonnie Ali placed a spotlight on the lifestyle of Parkinson's patients and their caregivers today at a press briefing to help raise awareness for the plight of Parkinson's disease patients across America. Currently it is estimated that one in every 100 people over the age of 60 are affected by the debilitating neurodegenerative disease that causes patients to lose muscle control. As the average age of the American population increases in the next decade, the number of people who will suffer from Parkinson's will also increase. Researchers are still searching for the cause of the disease. Parkinson occurs when the brain cells that create dopamine begin to die. Dopamine is the chemical that allows the brain to send messages to the body, allowing normal muscle movement. The loss of the dopamine causes Parkinson's symptoms that include a shuffled walk, shaking hands, drooling, slowed speech and frozen facial expression. "Our hope is to draw attention to the daily struggle of the average Parkinson's patient and caregiver as they work together each day to try and build more quality into their lives," explained Lonnie Ali. "Parkinson's patients need support. They need pharmaceutical companies to continue research for new medications and hopefully a cure. They need regulatory authorities to expedite the review process on new drugs in order to get them to patients quicker. They need the support of Congress. And, they need the media to help educate all Americans about this disease." Prior to the 1995 Olympic Summer Games in Atlanta, most people would not have been able to describe Parkinson's disease. But when Muhammad Ali took the torch and lit the Olympic flame, Parkinson's was defined for the world. One of the most charismatic, jubilant, energetic and athletic figures of the 20th Century was reduced to a shuffled walk, trembling hands and frozen facial expression. It was a disturbing, yet a courageous sight. On that Friday night in Atlanta, the champion of so many causes had lifted a large light onto Parkinson's disease. Today in Chicago, he shed more light onto the plight of the Parkinson's patient, when he and wife Lonnie explained the everyday battle of Parkinson's patients and their caregivers as they go the distance against the disease. "Muhammad has refused to let Parkinson's slow him down," said Lonnie, who travels with her husband throughout the world. "It's my job to make sure he gets the proper nutrition, takes his medication at the correct time each day, and exercises. He won't run anymore, because he realizes now how bad it is for his joints. We are planning to build a gym where he will workout daily, hitting the bag and sparring." Jack Reich, a Parkinson's patient from Skokie, Illinois, and Lydia Reich, his wife and caregiver, participated in the discussion with the Alis, sharing their personal story. "Jack is very active. I keep him going all day," said Lydia, who believes a busy schedule is important to his overall well-being. "If we don't have to go to the doctors, we go to the mall to walk. Twice a day at home, he rides his stationary bike, lifts weights, does paperwork, and moves around quite well on his walker. I keep him on a strict time schedule and diet. His new medication has made him feel a bit better." Both Muhammad Ali and Jack Reich were prescribed Mirapex when it was made available in July. Dr. Peter LeWitt of Wayne State University School of Medicine moderated the discussion about the lifestyle of Parkinson's patients with the Reichs and Alis. In addition, Dr. Baltazar Gomez-Mancilla, medical director of neurology for Pharmacia & Upjohn (NYSE: PNU), presented information about treatments for Parkinson's disease including the newly approved Mirapex (pramipexole dihydrochloride tablets), the first Parkinson's drug cleared for marketing (July 2, 1997) by the U.S. Food and Drug Administration in eight years. Patients should be informed that treatment with Mirapex, like all dopamine agonists, may cause hallucinations or postural hypotension. Pharmacia & Upjohn co-markets Mirapex with Boehringer Ingelheim Pharmaceuticals, Inc., which is based in Ridgefield, CT, and is the largest U.S. subsidiary of Boehringer Ingelheim Corporation. Boehringer Ingleheim Corporation is a member of the Boehringer Ingelheim worldwide group of companies headquartered in Ingelheim, Germany. A privately held company, founded in 1885, Boehringer Ingelheim is a major pharmaceutical, chemical, animal health, and bakery products manufacturer with operations in more than 100 countries around the world. Pharmacia & Upjohn is a global, innovation-driven pharmaceutical and health care company. Pharmacia & Upjohn's products, services and employees demonstrate its commitment to improve wellness and quality of life for people around the world. SOURCE Pharmacia & Upjohn, Inc. CO: Pharmacia & Upjohn, Inc.; Boehringer Ingleheim Corporation ST: Illinois, MichiganCA, Connecticut IN: MTC SU: