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In a message dated 97-09-09 15:41:58 EDT, you write: > Today is about 3 weeks after >beginning this trial and I am up to 3.75 mg per day total mirapex. But >what I find truly amazing is that for 3 days now I have not taken any >sinemet! It seems the mirapex must be potentiating my own endogenous >dopamine. I am also "on" all the time. In fact I wake up "on"" in the >morning. I have had PD for 16 years and have taken sinemet in one form or >another for over 14 years so this is truly amazing to me. Tom - What wonderful news! Please keep us posted as time goes by. It sounds as if you handled titrating the meds in a way that worked perfectly for you. Margie Swindler [log in to unmask]