 |
 |
A bit technical, but the words I understood sent a clear message: dietary Vit. E intake is important & beneficial. Abstracts - June 1997 Dietary Antioxidants and Parkinson Disease The Rotterdam Study Maarten C. de Rijk, MD; Monique M. B. Breteler, MD, PhD; Johanna H. den Breeijen, MSc; Lenore J. Launer, PhD; Diederick E.Grobbee, MD, PhD; Frans G. A. van der Meche, MD, PhD; Albert Hofman, MD, PhD Objective: To investigate whether high dietary intake of antioxidants decreases the risk of Parkinson disease (PD). Setting: The community-based Rotterdam Study, the Netherlands. Design: The cross-sectional study formed part of a large community-based study in which all participants were individually screened for parkinsonism and were administered a semiquantitative food frequency questionnaire. The study population consisted of 5342 independently living individuals without dementia between 55 and 95 years of age, including 31 participants with PD (Hoehn-Yahr stages 1-3). Results: The odds ratio for PD was 0.5 (95% confidence interval [CI], 0.2-0.9) per 10-mg daily dietary vitamin E intake, 0.6 (95% CI,0.3-1.3) per 1-mg beta carotene intake, 0.9 (95% CI, 0.4-1.9) per 100-mg vitamin C intake, and 0.9 (95% CI, 0.7-1.2) per 10-mg flavonoids intake, all adjusted for age, sex, smoking habits, and energy intake. The association with vitamin E intake was dose dependent (P for trend=.03). To assess whether the association was different in participants with more advanced disease, we excluded those with PD who had a Hoehn-Yahr stage of 2.5 or 3. This did not fundamentally alter the results. Conclusion: Our data suggest that a high intake of dietary vitamin E may protect against the occurrence of PD. Arch Neurol. 1997;54:762-765 Margaret Tuchman (55yrs, Dx 1980)- NJ-08540 [log in to unmask] Reposted by: Larry Fleming (Margaret, I hope you didn't mind me resubmitting this and I hope Donna appreciates it as much as I did when you submitted it in June) [log in to unmask] -----Original Message----- From: Parkinson's Information Exchange On Behalf Of Donna A. Bassolino Sent: Wednesday, September 10, 1997 2:17 PM To: Multiple recipients of list PARKINSN Subject: drugs/?/ & vitamins ? So what have we decided ? Vitamin B ... banana's or what ? I've read some good things about Vit E too - I've been thiking of getting some for my dad. My husbands grandmother has been taking it for YEARS and she's 92 !! So maybe she's onto something. The think that bothers me is the RDA is around 30 ... although some newer info puts it at 200. The ones in the drug store are 250-500 - Now i know too much of a good thing can be just as bad as not enough. Maybe I'll get him to get half (100) - every day or every other day ? Anybody out there have any stories on Vitamin E ? thanks have a nice day ! donna ------------------------------------------------------------------------------ * Donna Bassolino-Klimas, Ph.D. Bristol Myers Squibb Pharma. Res. Inst. Department of Macromolecular Structure P.O. Box 4000 Room H3812 Princeton, N.J. 08543 4000 (609) 252 4413 INTERNET: [log in to unmask] ------------------------------------------------------------------------------ * UPIMSRGSMTP01bnexu_f2krZiBywT?0SwBF8OiO-