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Date: Thu, 11 Sep 1997 11:20:03 -0400
From: tom riess <[log in to unmask]>
Subject: PARKINSN Digest - 10 Sep 1997 to 11 Sep 1997 - Special issue
To: "Parkinson's Information Exchange" <[log in to unmask]
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Ida Kamphuis.
Dear Ida, =
I believe I can answer at least one of your questions. I believe the
reason so many of us are better in the am, at least temporarily, is that
while we sleep we build up "unused" endogenous dopamine. I believe there=
is a relationship between the amount of activity we have and the rate of
dopamine consumption. Complete bed rest is the most conserving. So in=
the morning our reserves are the highest.
Also, I know of no one who has had PD for a substantial period of time wh=
o
has not increased his dose of L-Dopa.
Regards,
Tom
