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My mother Joyce (68/6 months) changed doctors recently. She was taking 25/100 Sinemet 4.5x/day, .25 Permax 5x/day, 10 mg. Paxil 1x/day. Her new doctor wanted to reduce the Sinemet a bit and start her on Eldepryl. This required her getting off the Paxil. About 4 days ago, she stopped the Paxil and started feeling shaky inside -- a nervousness that wouldn't quit. She decided today to continue the Paxil again (she hadn't started the Eldepryl) and felt better. She suspects this internal shakiness/nervousness is a side effect of the Permax. Any thoughts on this? Has anyone had a similar sensation? Was it related to a particular drug. Thanks. Debbie White [log in to unmask]