Hi ! I'm back I was off yesterday - to take my dad to the his neuro ... as you may recall he really hasn't been doing well lately and he can't go on like this (and neither can the rest of us). The dr.s keep saying its manageable and they'll help him but its been 10 months and he's no better ... and on some fronts even worse. So we went the the N yesterday full of hope ... we thought he was going to be put on Mirapex. The receptionist was telling us about 7 others they put on Mirapex that love it - were able to cut back and even ccut out Sinemet. They say they feel better than they ever did in years. Give us SOME ! But the N came in - looked over my dad's case - made him walk - talked about the nausea and depression and axiety ... and decided he didn't "want to add a new drug to the equation till it was sorted out" why he felt so sick etc. WHy he was nauseaous depressed etc. Suggested maybe changing the anti-depressant. SO becuase he was walking slow (which he wasn't really doing last week but of couse for the Dr - thats how he was walking) ... he wants to INCREASE his sinemet (he couldn't tolerate it last spring which was why it was CUT !) ITS THE SINEMET - STUPID ... sorry - but everyone says how nasty this drug is why not get him off it - or lower it or keep him on this low dose. Increasing it is only going to make him MORE miserable -and more depressed ! The N is supposed to get together with the family physician and figure something out. Now we saw the family phys (GP) last week - his opinion was that the Sinemet was making him sick and since the dose was low it was not helping his legs enough - and that of course was making him frustrated and depressed. Makes sence to me ! So he felt that getting him off the Sinemet (or onto the Mirapex) might reduce some of this and then the anti-depressant would work. Which is why we went to the N. So now we have two conflicting opinions - they're suposed to talk it out - but I don't know which side will win. Personnally I tend to agree with the GP. But we don't know what to do ... we came home yesterday VERY disappointed ! And of course my dad is more depressed and axious than ever. Now he thinks they really don't know what to do to helo him and are pushing him off to other dr.s. I don't know - it was very upsetting. Hmmm - as I write this I'm think - i don't know what I expect any of you to DO about this - but i guess the opportinity to vent and sympathetic ears helps ME. But it still doesn't help my dad ! thanks for listenting though ... any suggestions welcolm donna ------------------------------------------------------------------------------ - Donna Bassolino-Klimas, Ph.D. Bristol Myers Squibb Pharma. Res. Inst. Department of Macromolecular Structure P.O. Box 4000 Room H3812 Princeton, N.J. 08543 4000 (609) 252 4413 INTERNET: [log in to unmask] ------------------------------------------------------------------------------