Donna Bassolini wrote, "....... he wants to INCREASE his sinemet (he couldn't tolerate it last spring which was why it was CUT !) ITS THE SINEMET - STUPID ... sorry - but everyone says how nasty this drug is why not get him off it - or lower it or keep him on this low dose. Increasing it is only going to make him MORE miserable -and more depressed !". My mother (80,6) also found that sinimet was causing her to be nauseous, and she couldn't tolerate even a low dosage of the drug. She finally found a Parkinson Specialist who advised her to take Motilium. She now takes Motilium with each dosage of Sinimet (5 times a day 25/100), and has no troubles with nausea. Her walking and balance has greatly improved. And since she started on Mirapex, can now get on a bus and travel by herself. I hope this advice helps. [log in to unmask]