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Fri, 12 Sep 1997 07:39:36 -0400 From: Nancy Pearl Solomon <[log in to unmask]> Subject: speech/voice problems Dear Nancy, I wrote to you about a week ago giving you my ideas on the topic of speec= h in PD. Since that time I have found another approach which has come very= close to normalizing my speech. = I have had PD for some 16 years and have taken Sinemet in one form or anther for 14 years. Most recently I have been taking 15 to 18 50/200 CR'= s daily. However, about 3 1/2 weeks ago I began titrating myself onto Mirapex the powerful new D3 receptor site agonist. I am now up to about 4mg per day. More importantly I have been able to completely D/C my Sinemet, Parlodel and Amantadine. This is my 5th day without any Sinemet= =2E = During these past 5 days my speech has been very close to normal where before I was unintelligible the majority of the day. I can't of course s= ay this is a solution for everyone or even whether I will be able to remain off of Sinemet but it certainly is delightful for the present. Regards, Tom