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I switched from Zoloft to Serzone (nefazadone) and the results were less than desirable. I went back to Zoloft to regain my emotional stability. ...l weddel Margie Swindler wrote: > > Donna, you write: > > >Now I have more ?'s ... I mentioned that he was on Serzone - I thought it > >was helping - but my mom read something about too much SSRI's with PD not > >being good (although I know different ones are different - I know Buspar for > >example can block dopamine - but she just lumps them all together). Anyway > >she cut back one of his Serzone thinking this would ease his upset sick > >stomach > >and the fogginess he gets ... one less pill couldn't matter that much ? > >I think it did - I think he's much more depressed than before. > > Donna, I'm not familiar with Serzone. Is it another name for the generic > Sertraline Hydrochloride, brand name Zoloft? If so, it would be one of the > SSRIs. My husband takes Zoloft quite successfully, as do a number of other > PWP we know. He tried cutting back on it once, and knew within a few days > that he *really* needed to take it. Will you write and tell us the generic > name of Serzone and what type of drug it is, if you know it? > > SSRIs are not the same class of drugs as other antidepressants such as the > tricyclics. Buspar, which you also name, is a minor tranquilizer and > anti-anxiety drug, but is unrelated to the more common benzodiazepam family > of tranquilizers. Is your mother thinking that all anti-depressant and > tranquilizer drugs are SSRIs? I'd suggest that you talk to your local > pharmacist about any and all drugs your dad is taking, and ask for package > inserts for each one. > > One other suggestion based on our personal experience: we've found that > Dick's depression is almost entirely related to dopamine levels. If he can > get enough dopamine in his system without unbearable side effects, he isn't > depressed. For him, Mirapex was the answer, although it doesn't seem to be > the answer for everyone. > > Jerry, if you're around, this - antidepressants - would be a good subject > for you to address.... > > Margie Swindler [log in to unmask]