---------- > Fra: Mary Legan <[log in to unmask]> > Til: Multiple recipients of list PARKINSN <[log in to unmask]> > Emne: Internal shakiness > Dato: 13. september 1997 03:45 > > I'm glad this topic has been brought up, as I too have very much wanted an > explanation of this phenomenon. I experienced this before my PD diagnosis, > when I described it to my neuro (who was treating me for migraines & > insomnia) as an "internal revving motor..........at that time I was taking a > low dose of Sinequon with Xanax......then the Xanax was replaced with Buspar > (needless to say, my "anxiety" didn't improve). At that same time, I was > experiencing hot flashes, etc. because of menopausal hormonal fluctuations, > which may or may not be relevant. When I then received the pd dx, I was > started on Sinemet, Paxil, & Trazadone (for sleep). No further problems with > internal shakiness until several months ago. At the time I was taking > estrogen & progesterone, & having severe daily migraines. Also, the internal > revving was happening again, & a difficulty which I don't remember having > before - the need to breathe deliberately & deeply. After some ado, I > discontinued the hormones ~6 wks ago. The migraines have shown moderate > improvement, but the other symptoms remain. I'm hoping that soon whatever > confounding effects the hormones have contributed will be out of the picture. > It will make things much easier if whatever symptoms remain can clearly be > tied to the pd. Perhaps one or more of our list members can at least explain > the internal shakiness, for my benefit & for the others who experience this. > Explanations of the other issues I mentioned are also most welcome! Mary > Legan 55/5+ Hello Mary, Just to tell you that one of my sympt. was internal shakiness, and my GR doctor tried to give me Beta-Block but it didn`t help me because I wasn`t nervous, three month later I had the diagnose, it`s now 4 years ago, and sometimes I still have it, but now I know was it is. Greetings Sonia Nielsen Denmark NEVER GIVE UP > > <My mother Joyce (68/6 months) changed doctors recently. She was taking > 25/100 Sinemet 4.5x/day, .25 Permax 5x/day, 10 mg. Paxil 1x/day. Her new > doctor wanted to reduce the Sinemet a bit and start her on Eldepryl. This > required her getting off the Paxil. About 4 days ago, she stopped the Paxil > and started feeling shaky inside -- a nervousness that wouldn't quit. She > decided today to continue the Paxil again (she hadn't started the Eldepryl) > and felt better. She suspects this internal shakiness/nervousness is a side > effect of the Permax. Any thoughts on this? Has anyone had a similar > sensation? Was it related to a particular drug. Thanks. > > > Debbie White > [log in to unmask]