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In a message dated 97-09-22 16:59:42 EDT, you write: << I've discussed liquid Sinemet and the issue of frequent smaller doses of Sinemet vs. less frequent larger doses with two neuro's at the Kansas University Neurological Foundation. Both are widely known PD and movement disorder specialists who see a number of other List members. My understanding from both conversations is that the body responds more predic >> This is typical of the general confusion among neurologists, most of whom are primarily interested in the more exciting field of early parkinsons where there are many promising things in the offing. Our experience with liquid sinemet came as a result of a recommendation from the Movement Disorder Center at the University of Southern Florida in Tampa. Ask your Kansas neurologist if he/she has worked with any parkinsons patient for more than five, ten, 15, 20, or more years.