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Charlie and Nigel -
I asked Dr. Schumaher this same question.... Would the pallidotomy preclude
Bob from any future, better, treatments?  Dr. Schumacher said he thought
not, because so many PD patients are getting the pallidotomy that whatever
future "treatment", whether it be a drug or a new surgical procedure, would
surely be tested on the "pallidotomy patients"   a/k/a   "hole in the head
gang".  I think he may be right.  Bob added that even if the pall. does
exclude him he does not care, Bob said that since this disease he has
learned to "live for each day".  I am sure some doctors will want to do a
study on the "hole in the head gang"  to see how the new future
drug/procedure  affects them.

Just my opinion,
Jackie

From: Charles T. Meyer <[log in to unmask]>



>Nigel-
>
>I think you are asking exactly the right question.  I had considered a
>palidotomy several years ago.  I was told that it would make me
>ineligible for other research procedures.  Since then I haVE BEEN A
>PARTICIPANT IN AN eTACAPONE STUDY AND A FETAL TRANSPLANT STUDY.  I made
>the decision about the palidotomy because some adjustment of my meds at
>the time made me relatively functional.  I am 52 so your caution makes
>even more sense.  If your symptoms are significantly disabling and
>cannot be significantly improved with a med change,  then I would go
>with the pallidotomy,  but if you can waif without sacraficing quality
>of present if too much I think you would be wise to wait,
>
>Charlie
>
>Nigel Harland wrote:
>>
>> Hello,
>>         AT my most recent meeting with my neuro', he suggested I consider
>> having a Pallidotomy, which after reading all the various comment from
>> listmembers, seems like a positive move. However, there is one aspect of
>> the operation which concerns me,and that is with the advent of the
research
>> into Brain cell regeneration drugs i.e. GPI-1046, would having had a
>> pallidotomy have an adverse effect on a potential recovery should these
>> drugs become available? I know that research into GPI-1046 is still in
its
>> infancy, but at the age of 42 I don't want to make a decision now that I
>> might regret for a long time.
>> Regards,
>> [log in to unmask]
>
>--
>
>CHARLES T. MEYER, M.D.
>Middleton, WI
>[log in to unmask]
>