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On Fri, 19 Sep 1997 09:26:22 -0400 LISA CRUMRINE <[log in to unmask]>
wrote:
>hello from the caribean.  My question is regarding the meds i'm taking
>6am: 1 sinemet cr 25/100
>     1 permax .25
>     1 eldepryl
>then every three to 4 hours i take a sinemet cr25/100 and a permax .25
>
>lately i have been getting some new side effects,  my left side has
>uncontrolable jerky movements and shaking. and i have been getting a
>really speedy feeling, really hyper, like 5 cuops of coffee.  these
>are new symptons.  the good news is that the toe curl and stifness is
>lesser than it was.  am i taking too much of something, or is this
>just part of the wonderful parkinsons experience?   help.
>
>regards
>
>lisa in paradise
>
Hello Lisa, One comment that you made strikes me as a possible cause of
your new symptoms. (Ivan may be correct; it could be the Eldepryl) .You
should be aware that Sinemet CR has a typical duration of 4 hours. You
mention taking your CR tablets "every 3 or 4 hours". You need to be very
careful about that overlap: If you take your second tab 3 hours after the
first one, you could have an hour during which you are effectively
double-dosed, which could easily result in what sound like Dyskinesias.
When I used to take the CR tabs, I found it safer to slip an ordinary
Sinemet in between each CR (allowing 2 hours for the ordinary Sinemet)
because if I made a mistake and got 2 CR tabs overlapping, the distress
resulting from the overlap seemed to last for ages. The CR Tabs can be
very useful, but need to be treated with respect and care.

Regards,
--
Brian Collins  <[log in to unmask]>