On Fri, 19 Sep 1997 09:26:22 -0400 LISA CRUMRINE <[log in to unmask]> wrote: >hello from the caribean. My question is regarding the meds i'm taking >6am: 1 sinemet cr 25/100 > 1 permax .25 > 1 eldepryl >then every three to 4 hours i take a sinemet cr25/100 and a permax .25 > >lately i have been getting some new side effects, my left side has >uncontrolable jerky movements and shaking. and i have been getting a >really speedy feeling, really hyper, like 5 cuops of coffee. these >are new symptons. the good news is that the toe curl and stifness is >lesser than it was. am i taking too much of something, or is this >just part of the wonderful parkinsons experience? help. > >regards > >lisa in paradise > Hello Lisa, One comment that you made strikes me as a possible cause of your new symptoms. (Ivan may be correct; it could be the Eldepryl) .You should be aware that Sinemet CR has a typical duration of 4 hours. You mention taking your CR tablets "every 3 or 4 hours". You need to be very careful about that overlap: If you take your second tab 3 hours after the first one, you could have an hour during which you are effectively double-dosed, which could easily result in what sound like Dyskinesias. When I used to take the CR tabs, I found it safer to slip an ordinary Sinemet in between each CR (allowing 2 hours for the ordinary Sinemet) because if I made a mistake and got 2 CR tabs overlapping, the distress resulting from the overlap seemed to last for ages. The CR Tabs can be very useful, but need to be treated with respect and care. Regards, -- Brian Collins <[log in to unmask]>