Romona, I am NOT a medically trained person, but I have to ask a question, in case it might be of help. Have you ruled out the atmosphere of your home as a cause or irritant for the boys problems? I am thinking about things like radon from the ground that seeps into the house, also certain insects, I think it includes roaches, even when they are dead, are said to affect, or maybe even cause, asthma. Good luck, you sound like a great mother, who will take care of everything. Ken B