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Thank you to all who replied to my concerns regarding the 1.5mg level of Mirapex dosage. With the knowledge gleaned from all your comments, and no objections from our neuro, we have dropped back to .75mg daily. Jim feels enormous fatigue, still, and some general malaise (feeling "overmedicated"), but it's better than before, and symptom control remains constant. We are pleased to be able to delay sinemet introduction for as long as possible, too. Thanks again, everyone. Emily Jackson, CG Jim, 69/1+ Emily Jackson [log in to unmask]