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Clara, please don't take offense at my blaming hormones for a bad situation, I would RATHER think Michael's wife is an innocent victim of a medical condition, then just being a bad person! My wife and my daughter have two definite personalities, depending on their hormone levels. YES, men have changes in middle age, due to hormone levels, I have been taking DHEA, and I feel like I am being helped with MY hormonal changes. I have not done any "middle age crazy" stuff..yet.....I also do not think a man OR a woman has to be out of control, or have hormone problems, if they are just tired of a spouse, or stressed out by life's problems which appear to be related to being married. Ken B