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Clara N.... Clara, m'dear, I took Midrin for migraine (which I rarely get any more, having gone to a migraine clinic 20 years ago) many years ago for a several years. The drug was excellent for alleviating the migraines as a rule. HOWEVER... as a person with Parkinson's, I wouldn't TOUCH Midrin NOW with the proverbial ten-foot-pole! I strongly feel that it could enhance the negative effects of PD by causing additional movement problems. This feeling is based upon how my movement was originally effected by the drug when I took it fairly regularly years ago. Taking the Midrin ALWAYS altered my movements a bit... got kind "jerky" and my balance was affected as well. Since both those symptoms are inherent with PD, who knows if the drug didn't speed up the onset of the disease (I'm NOT saying it GAVE me the PD tho!), or otherwise affect it even tho at that time I didn't KNOW I would be coming down with the disease within a few short years.. Food for thought regarding PD, migraines and Midrin. Barb Mallut [log in to unmask] ---------- From: Parkinson's Information Exchange on behalf of cln Sent: Sunday, September 28, 1997 10:30 AM To: Multiple recipients of list PARKINSN Subject: Re: Meds 4 migraine headaches Hi Mary & all! Decided to include all of you with the following information. Never know when there may be a shy guy/gal in the group who may have an interest. The past five years, I've taken 2 capsules of Midrin plus 1 capsule of a generic called Naproxen (Anaprox) beginning at the first signs of a pending headache. I repeat with 1 Midrin in 1 or 2 hours if necessary. (The key to success is to take both medications at the very first sign.) The Naproxen (500 MG) can be repeated 8 hours later. But since I'm highly sensitive to meds, I never usually have to repeat the Naproxen because my headache usually is gone by then. The only caution and warning I read about Naproxen is: "Do not take Naproxen if you are alergic or sensitive to this drug, Aspirin, or other NSAIDs (One of several nonsteroidal anti-inflammatory drugs used to reduce inflammation, relieve pain, or reduce fever. All NSAIDs share the same side effects and may be used by patients who cannot tolerate Aspirin.) Naproxen may cause stomach ulcers. This drug should not be used by patients with severe kidney or liver disease." The only info I have on Midrin is that it is a brand-name drug containing an analgesic and it's a sedative drug used for migraine. As mentioned, I'm not a PWP. However, the combination of these two prescription drugs works for me. Wishing you a "goodbye to headaches forever". Clara Nistler 62 Gene Nistler 64/11