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Ivan, the low blood pressure is almost certainly the reason for the fatigue, and the increased depression. Those are come pretty low numbers. I encourage you to take Camilla's advice and check out that drug. Low blood pressure makes you cold too, and you do live in ME !! Weren't you taking NADA ? I thought you raved about how energetic you felt. On balance, do you think taking it was worth it? Well, at least you don't have high blood pressure. Please keep us posted. Bruce A. (51,3)