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There should be no problem in taking the generic drug especially when she is starting with it early in treatment. Most generics are identical and are often made on the same production line as the "brand name" drugs. Occasionally there will be a question about bioavailability with a particular drug but even that is controlled for if she sticks to the same generic. Also Sinemet is a combination of Carbidopa and levodopa. The carbidopa (given to prevent metabolism of the levodopa before it gets to the brain) is the first number and levodopa dose the second. Charlie Kathy Barras wrote: > > Mom started taking Sinemet 10/100 3x per day about 3 weeks ago. When I > had the prescription filled the pharmacy asked if generic would be ok? > > Any comments/opinions on Sinemet vs. generic(whatever that may be)? > > Also, what does 10/100 represent? > > Thanks in advance! > > Kathy Barras cg mom(73/3 weeks) > [log in to unmask] -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]