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Nausea is also common with madopar. I too suffer depression and take prozac which helps a lot. But I really havent had a good night sleep for years. I have lost 42 pounds in weight in recent months even though I eat well. I know of other Parkies who have also lost weight. Even taking food suppelments has not helped so perhaps I am destined to be a like a stick. I have learned a lot since being on this listserve and would like to thank you all for the snippets of info. Keep smiling Nancy Stephenson (sticky0123) @aolcom