When my husband had a major depression 17 years ago, he was treated by a psychiatrist with antidepressants and psychotherapy until he and the psychiatrist thought he was recovered. Since My husband was a judge, the Dr. talked to his clerk who said he was still looking and acting depressed in court.( no facial expression, walking slowly and stooped, and no longer speaking with his usual light hearted speaking voice). The Psychiatrist immemediately referred us to a Neurologist who Immediately diagnosed PD and put my husband in sinemet. Within a week all symptoms disappeared along with some others we hadn't paid that much attention to. For four years, he had no symtoms unless he forgot his sinemet. Then he started to have all the problems you read about in this list until now he takes many meds and has dementia and shy drager syndrome in addition to advanced PD. We have full-time help now, and he stll enjoys seeing his family and those friends who can come to visit. Barbara Smith, CG/Ken/69/16